Frovatriptan vs. transdermal oestrogens or naproxen sodium for the prophylaxis of menstrual migraine

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A review of frovatriptan for the treatment of menstrual migraine

The objective of this review is to provide an overview of menstrual migraine (MM) and of frovatriptan and to assess clinical trial data regarding the efficacy and safety of frovatriptan for the acute and short-term prophylaxis of MM. Randomized controlled trials comparing frovatriptan with placebo or a triptan comparator for the acute or prophylactic treatment of MM were selected for review. MM...

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Frovatriptan: A Review of Pharmacology, Pharmacokinetics and Clinical Potential in the Treatment of Menstrual Migraine

Frovatriptan is an orally active 5-hydroxytryptamine (5-HT) receptor agonist which binds with high affinity to 5-HT(1B) and 5-HT(1D) receptors. Earlier clinical trials demonstrated that frovatriptan 2.5 mg is significantly more effective than placebo in the acute management of migraine and its associated symptoms. More recently, frovatriptan was shown to be effective in the management of menstr...

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Symptomatic or prophylactic treatment of weekend migraine: an open-label, nonrandomized, comparison study of frovatriptan versus naproxen sodium versus no therapy

BACKGROUND Migraine often occurs during weekends. The efficacy of frovatriptan, naproxen sodium, or no therapy for the acute or prophylactic treatment of weekend migraineurs was tested in an open-label, nonrandomized pilot study. METHODS Twenty-eight subjects (mean age 36 ± 12 years, including 18 females) suffering from migraine without aura were followed up for six consecutive weekends. No t...

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Prevention of migraine headache attacks: enalapril or valproat sodium

The pharmacological treatment of migraine may be acute or preventive. Frequent, Severe, complicated and long lasting migraine attacks, more than 2 attacks in month require prophylaxis. Traditional preventive drugs such as ?-Blockers, antidepressants, calcium blockers and anticonvulsants, despite their documented efficacy, have many side effects. This study was conducted to determine the effect ...

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Prevention of migraine headache attacks: enalapril or valproat sodium

The pharmacological treatment of migraine may be acute or preventive. Frequent, Severe, complicated and long lasting migraine attacks, more than 2 attacks in month require prophylaxis. Traditional preventive drugs such as ?-Blockers, antidepressants, calcium blockers and anticonvulsants, despite their documented efficacy, have many side effects. This study was conducted to determine the effect ...

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ژورنال

عنوان ژورنال: The Journal of Headache and Pain

سال: 2007

ISSN: 1129-2369,1129-2377

DOI: 10.1007/s10194-007-0417-4